We hear people say that "the air gets thin" as we climb up mountains. We hear information about oxygen masks when we ride in planes, and mountain climbers take oxygen with them as they climb high peaks.
What does all this really mean?
Let's think about the air that we are breathing. How much air do we take in at a breath? An average woman takes in 4.5 liters. Athletes may take in 6 liters or more. (The cyclist Miguel "Big Mig" Indurain has a lung capacity of 7.8 meters!) Let's go with 5 liters per breath to make the math simple.

One atmosphere = 14.7 pounds of pressure per square At sea level, air pressure on earth is called one atmosphere.inch.
When you take a 5 liter breath at one atmosphere you are taking in
760 mm of mercury = 1 atmosphere of pressure
A scientist called Robert Boyle (1627-91)worked with gases. He came up with Boyle's Law which says that
Pressure multiplied by volume = mass multiplied by (a constant) multiplied by temperature
PV=nrt
n=the mass, i.e., the number of moles
a mole = the number of molecules is 6.023*10^23
1 mole = 24 liters of atmospheric gas at sea level at 25 degrees celsius
50 billion molecules; volume of 8 liters at 5 atmospheres of pressure
10 billion molecules; volume of 8 liters at 1 atmospheres of pressure